Use of oxidized lipoproteins for differentiation of precursor cells into mature dendritic cells
US7259012B2 · kind B2 · utility
0Cited by
3References
20Claims
0Family size
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Key dates
| Filing date | Jul 8, 2002 |
| Grant date | Aug 21, 2007 |
| Priority date | — |
| Expiry date | Jun 13, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2500/36
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns a method for differentiating precursor cells into mature dendritic cells, comprising placing the precursor cells in a medium suitable for their differentiation and adding to the medium, in a predetermined amount, at least one fraction of oxidized lipoproteins selected among oxidized very low density lipoproteins (VLDLs) and/or oxidized intermediate density lipoproteins (IDLs) and/or oxidized low density lipoproteins (LDLs). The precursor cells are preferably monocytes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.