Vector system
US7259015B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 7, 2003 |
| Grant date | Aug 21, 2007 |
| Priority date | — |
| Expiry date | Dec 28, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/206
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are retroviral vector genomes and vector systems comprising the genomes. In particular, a retroviral vector genome comprising two or more NOIs, operably linked by one or more Internal Ribosome Entry Site(s); a lentiviral vector genome comprising two or more NOIs suitable for treating a neurodegenerative disorder; and a lentiviral vector genome which encodes tyrosine hydroxylase, GTP-cyclohydrolase I and, optionally, Aromatic Amino Acid Dopa Decarboxylase are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.