AAV virions with decreased immunoreactivity and uses therefor
US7259151B2 · kind B2 · utility
32Cited by
1References
24Claims
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Key dates
| Filing date | Jun 21, 2004 |
| Grant date | Aug 21, 2007 |
| Priority date | — |
| Expiry date | Jun 21, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/85
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of making and using recombinant AAV virions with decreased immunoreactivity are described. The recombinant AAV virions include mutated capsid proteins or are derived from non-primate mammalian AAV serotypes and isolates that display decreased immunoreactivity relative to AAV-2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.