Methods for producing preparations of recombinant AAV virions substantially free of empty capsids
US7261544B2 · kind B2 · utility
7Cited by
1References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 21, 2004 |
| Grant date | Aug 28, 2007 |
| Priority date | — |
| Expiry date | Aug 26, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16051
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for separating AAV empty capsids from mixtures of AAV vector particles and AAV empty capsids are described. The methods use column chromatography techniques and provide for commercially viable levels of recombinant AAV virions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.