Neutralizing antibodies against GDF-8 and uses therefor
US7261893B2 · kind B2 · utility
185Cited by
16References
21Claims
0Family size
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Key dates
| Filing date | Oct 21, 2003 |
| Grant date | Aug 28, 2007 |
| Priority date | — |
| Expiry date | Jun 1, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/622
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), in particular human antibodies, and antibody fragments, including those that inhibit GDF-8 activity in vitro and/or in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle or bone, or disorders of insulin metabolism.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.