System and methods for detection of Bacillus anthracis related analytes in biological fluids
US7262019B2 · kind B2 · utility
14Cited by
26References
27Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 24, 2004 |
| Grant date | Aug 28, 2007 |
| Priority date | — |
| Expiry date | May 24, 2024 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides a heterogeneous immunoassay for detection of antibodies and antigens based on specific antigen-antibody immune complex formation with multiple antigen-bearing conjugate components. The invention further provides means for optimizing the assay format for the detection of both low and high-affinity antibodies, and provides means for quantitative detection of both antibody and the corresponding antigen present in a sample. In preferred embodiments, the invention can be practiced to detect presence in biological fluid samples of antibodies to Bacillus anthracis related antigens.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.