Chemosensitizing with liposomes containing oligonucleotides
US7262173B2 · kind B2 · utility
7Cited by
32References
12Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Feb 15, 2002 |
| Grant date | Aug 28, 2007 |
| Priority date | — |
| Expiry date | Nov 3, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/345
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the use of oligonucleotide containing cationic liposomal formulations to enhance the efficacy of chemotherapy and/or radiotherapy, particularly as a means to sensitize cancerous tumor tissues to the efficiencies of chemotherapy. This is particularly advantageous in the context of treating raf expressing tumors such as breast, lung, pancreatic and prostate tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.