Synthetic oligonucleotides as inducers of erythroid differentiation
US7262175B2 · kind B2 · utility
1Cited by
2References
9Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Mar 13, 2001 |
| Grant date | Aug 28, 2007 |
| Priority date | — |
| Expiry date | Sep 16, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention refers to a synthetic double-stranded oligonucleotide having a length comprised between 10 and 50 bases and a nucleic acid sequence selected from the group consisting of: (a) sequences corresponding to a selected portion of the promoter of human γ-globin gene; and (b) sequences corresponding to a selected portion of the human genomic region comprised between the γ-globin gene and the δβ-cluster, for use as an inducer of erythroid differentiation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.