Urea- and urethane-substituted acylureas, process for their preparation and their use

US7262220B2 · kind B2 · utility

Assignee

• Sanofi-Aventis Deutschland GMBH · DE

Inventors

• Elisabeth Defossa · Idstein, DE
• Dieter Kadereit · Kelkheim, DE
• Thomas Klabunde · Frankfurt, DE
• Hans-Joerg Burger · Morristown, US
• Andreas Herling · Bad Camberg, DE
• Karl-Ulrich Wendt · Frankfurt, DE
• Erich Roedern · Hattersheim, DE
• Karl Schoenafinger · Alzenau, DE

Key dates

• Filing date: Jul 11, 2003
• Grant date: Aug 28, 2007
• Expiry date: Dec 6, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D295/135
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to urea- and urethane-substituted acylureas and to their physiologically tolerated salts and physiologically functional derivatives. In particular, the invention relates to the compounds of the formula Iwherein the radicals have meanings described herein, and to their physiologically tolerated salts and to processes for their preparation. The compounds are suitable for example as antidiabetics.