Amidine derivatives for treating amyloidosis
US7262223B2 · kind B2 · utility
10Cited by
76References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 23, 2004 |
| Grant date | Aug 28, 2007 |
| Priority date | — |
| Expiry date | Jan 23, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/155
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the use of amidine compounds in the treatment of amyloid-related diseases. In particular, the invention relates to a method of treating or preventing an amyloid-related disease in a subject comprising administering to the subject a therapeutic amount of an amidine compound. Among the compounds for use according to the invention are those according to the following Formula, such that, when administered, amyloid fibril formation, neurodegeneration, or cellular toxicity is reduced or inhibited:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.