Method for the simultaneous dissection in specific positions of filiform organic molecular chains, in particular DNA

US7263445B2 · kind B2 · utility

Assignee

• Karsten Koenig · DE

Inventors

• Wolfgang Fritzsche · Jena, DE
• Karsten Koenig · Riegelsberg, DE
• Johann Koehler · Golmsdorf, DE

Key dates

• Filing date: Dec 12, 2001
• Grant date: Aug 28, 2007
• Expiry date: Apr 20, 2023

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S977/81
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to a method for the simultaneous dissection in specific positions of filiform organic molecular chains, in particular DNA. The aim of the invention is to provided a method, by which a highly specific dissection can take place on certain sequences that can be freely selected and simultaneously on numerous filiform molecules. To achieve this, nanoparticles (1) are provided with a molecular chain (11) of any predeterminable sequence, which is selected to be complementary to a sequence of a molecule (2) that is to be dissected, said molecular chain(s) (11) is/are hybridised in the usual manner with the molecule, or specifically linked to said molecule in another manner and the nanoparticles (1) are subsequently subjected to a high-energy radiation of at least one wavelength, which can be absorbed by said nanoparticles (1).