Patent · US Expired

Aryl and heteroaryl substituted tetrahydroisoquinolines and use thereof

US7265116B2 · kind B2 · utility

12Cited by
17References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 13, 2004
Grant dateSep 4, 2007
Priority date
Expiry dateAug 13, 2024

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D413/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are compounds of the formula (I):wherein R1-R8 are as described herein, R4 being phthalazinyl, pyrazinyl, pyridazinyl, or quinoxalinyl. Such compounds are particularly useful in the treatment of a disorder which is created by or is dependent upon decreased availability of serotonin, norepinephrine, or dopamine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.