Inhalation particles incorporating a combination of two or more active ingredients

US7267813B2 · kind B2 · utility

Assignee

• ORION CORPORATION · FI

Inventors

• Wiwik Watanabe · Sunnyvale, US
• Esko I. Kauppinen · Helsinki, FI
• Petri Ahonen · Jyväskylä, FI
• David P. Brown · Salt Lake City, US
• Esa Muttonen · Espoo, FI

Key dates

• Filing date: Oct 5, 2001
• Grant date: Sep 11, 2007
• Expiry date: Jan 20, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P37/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Crystalline spherical inhalation particles incorporating a combination of two or more different active ingredients and a process for the preparation thereof. The particles have a narrow particle size distribution, rough surfaces and improved stability. The inhalation particles of the invention are particularly useful in the administration of a combination medicament, e.g. a combination of an anti-inflammatory agent and a bronchodilator, by inhalation in the treatment of asthma and other respiratory disorders.