Patent · US Expired

Nucleic acid encoding pyruvate carboxylase from coryneform glutamicum

US7267967B1 · kind B1 · utility

4Cited by

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5Claims

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Assignee

Forschungszentrum Jülich GmbH · DE

Inventors

Bernd Eikmanns · Ulm, DE
Petra Peters-Wendisch · Bensberg, DE
Hermann Sahm · Jülich, DE

Key dates

Filing date	Sep 30, 1998
Grant date	Sep 11, 2007
Priority date	—
Expiry date	Sep 30, 2018

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y604/01001
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A pyruvate carboxylase gene having SEQ ID NO:1 as well as an amino acid sequence having SEQ ID NO:2 expressed by the pyruvate carboxylate gene are disclosed. Also disclosed is a method for microbial production of amino acids of the aspartate and/or glutamate family in which the pyruvate carboxylase activity is increased by genetically changing the pyruvate carboxylase gene having SEQ ID NO:1 through expression of a microorganism which produces the corresponding amino acid having SEQ ID NO:2.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.