Chimeric avidin mutants
US7268216B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Dec 29, 2005 |
| Grant date | Sep 11, 2007 |
| Priority date | — |
| Expiry date | Dec 29, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/465
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to new chimeric mutants of avidin protein with improved properties, e.g. thermostability, better stability against proteolysis, better charge properties (for example lower pl) compared to native avidin and avidin-related proteins, AVRs. The chimeric avidin mutants comprise mutants where a region or regions in avidin are substituted by a corresponding region or regions from an AVR protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.