Patent · US Expired

Method for the production of 4-(17$g(a)-methyl substituted 3-oxoestra-4 9-dien-11$g(b)-yl)benzaldehyd-(1e or 1z)-oximes

US7268241B2 · kind B2 · utility

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1References

20Claims

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Assignee

SCHERING CORPORATION · US

Inventors

Gerd Schubert · Jena, DE
Sven Ring · Jena, DE
Bernd Erhart · Kahla, DE
Gerd Mueller · Hamburg, DE

Key dates

Filing date	Nov 9, 2001
Grant date	Sep 11, 2007
Priority date	—
Expiry date	Oct 4, 2023

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention relates to a process for the production of 4-(17α-methyl-substituted 3-oxoestra-4,9-dien-11β-yl)benzaldehyde-(1E or 1Z)-oximes of general formula (I), in which R1 is a hydrogen atom, a C1-6-alkyl radical or a CnF2n+1 radical, whereby n is 1, 2 or 3, R2 is a C1-4-alkyl radical, X is an OH group in E- or Z-position, and Y is an OC1-6-alkyl group, an SC1-6-alkyl group or an OCH2CnF2+1 group, whereby n is 1, 2 or 3, which provides the target compounds of formula (I) with a high yield and good selectivity

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.