Multivalent streptococcal vaccine compositions and methods for use
US7270827B2 · kind B2 · utility
5Cited by
38References
15Claims
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Key dates
| Filing date | Oct 28, 2002 |
| Grant date | Sep 18, 2007 |
| Priority date | — |
| Expiry date | Aug 24, 2024 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/825
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods for making and using therapeutic formulations of multivalent hybrid polypeptides comprising immunogenic peptides of M proteins from various different serotypes of group A streptococci and antibodies thereto are provided. Also provided are nucleic acids encoding such hybrid polypeptides. The hybrid polypeptide formulations may be used, for example, in methods for treating or preventing a microbial infection and eliciting a protective immune response having broadly protective opsonic antibodies in the absence of tissue cross-reactive antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.