Electrical field stimulation of eukaryotic cells
US7276206B2 · kind B2 · utility
31Cited by
10References
7Claims
0Family size
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Key dates
| Filing date | Jul 12, 2002 |
| Grant date | Oct 2, 2007 |
| Priority date | — |
| Expiry date | Sep 1, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/11
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods of identifying activators and inhibitors of voltage-gated ion channels are provided in which the methods employ electrical field stimulation of the cells in order to manipulate the open/close state transition of the voltage-gated ion channels. This allows for more convenient, more precise experimental manipulation of these transitions, and, coupled with efficient methods of detecting the result of ion flux through the channels, provides methods that are especially suitable for high throughput screening.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.