Nucleic acids encoding endotheliases, endotheliases and uses thereof
US7276364B1 · kind B1 · utility
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56References
32Claims
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Key dates
| Filing date | Nov 20, 2000 |
| Grant date | Oct 2, 2007 |
| Priority date | — |
| Expiry date | Nov 20, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are endotheliases and portions, particularly, the protease domains, and nucleic acids that encode the endotheliases. The endotheliases are transmembrane proteases expressed in endothelial cells. The nucleic acids and encoded proteins and protease domain portions thereof are used in a variety of prognostic, diagnostic, therapeutic and screening methods, including methods for screening for compounds that modulate angiogenesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.