Patent · US Expired

Dipeptide inhibitors of β-secretase

US7276484B2 · kind B2 · utility

4Cited by
2References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 8, 2005
Grant dateOct 2, 2007
Priority date
Expiry dateMar 8, 2025

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K5/0205
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Dipeptide derived inhibitors of the β-secretase enzyme are provided which are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of Aβ peptide in a mammal. The compounds of the invention provide useful methods of treatment by administration of these inhibitors to reduce Aβ peptide formation and in pharmaceutical compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.