Methods for fine powder formation
US7278843B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 20, 2002 |
| Grant date | Oct 9, 2007 |
| Priority date | — |
| Expiry date | May 27, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1658
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Improved methods for forming fine particles of a material have been developed, wherein the method steps include dissolving the material in a solvent to form a dilute solution, immobilizing the dilution solution, and then removing the solvent to yield particles of the material. Methods of immobilizing the dilute solution include freezing, gelation, and chelation. In a preferred embodiment, the immobilized solvent is removed by lyophilization, i.e. reducing the ambient pressure while avoiding application of sufficient heat to power a phase transition. Essentially any material and solvent for the material can be used in the methods described herein. Proteins and peptides in an aqueous solvent are the preferred systems.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.