Patent · US Expired

Method of diagnosing epilepsy

US7282336B2 · kind B2 · utility

14Cited by

1References

3Claims

0Family size

Assignee

Bionomics Limited · AU

Inventors

Robyn Heather Wallace · Brisbane, AU
John Charles Mulley · Adelaide, AU
Samuel Frank Berkovic · Melbourne, AU

Key dates

Filing date	Oct 31, 2005
Grant date	Oct 16, 2007
Priority date	—
Expiry date	Oct 31, 2025

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

An isolated nucleic acid molecule encoding a mutant alpha subunit of a mammalian voltage-gated sodium channel, wherein a mutation event selected from the group consisting of point mutations, deletions, insertions and rearrangements has occurred and said mutation event disrupts the functioning of an assembled sodium channel comprising this mutated subunit so as to produce an epilepsy phenotype, polypeptides encoded by said nucleic molecule and uses of these molecules in preparing animal models and in diagnostic applications.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.