Patent · US Active

Nucleic acid molecule comprising a nucleic acid sequence which codes for a haemocyanin

US7282578B2 · kind B2 · utility

0Cited by

3References

31Claims

0Family size

Assignee

Biosyn Arzneimittel GmbH · DE

Inventors

Jürgen Markl · Gau-Bischofsheim, DE
Benjamin Altenhein · Wiesbaden, DE
Bernhard Lieb · Mainz, DE
Thomas Stiefel · Stuttgart, DE

Key dates

Filing date	Aug 29, 2006
Grant date	Oct 16, 2007
Priority date	—
Expiry date	Aug 29, 2026

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S530/855
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A nucleic acid molecule or construct alone or with a promoter suitable for expression control is contemplated that codes for a KLH1 haemocyanin, a haemocyanin domain or a fragment thereof with the immunological properties of at least one domain of haemocyanin, and comprises at least one intron sequence, as well as haemocyanin fusion proteins. The construct can also comprise a nucleic acid sequence that codes for an antigen. Host cells are also contemplated that contain the nucleic acid molecule or construct and a recombinant expression product thereof. The invention further relates to a pharmaceutical composition that comprises the expression product and antibodies obtainable by immunization of an animal therewith, as well as the use of antibodies in screening methods for the identification of tumors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.