Heteroaromatic urea derivatives as VR-1 receptor modulators for treating pain
US7285563B2 · kind B2 · utility
1Cited by
2References
12Claims
0Family size
Inventors
Key dates
| Filing date | Mar 21, 2003 |
| Grant date | Oct 23, 2007 |
| Priority date | — |
| Expiry date | Dec 28, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds of formula (I); pharmaceutically acceptable salts and N-oxides thereof in which A, B, D and E are C or N with the proviso that one or more are N, R1, R2, R3, R4, R5 and R6 are simple substituents, n is 0-3 and y is an aryl, heteroaryl, carbocyclyl or fused-carbocyclyl group; as VR-1 antagonists for treating conditions or diseases in which pain and/or inflammation predominates; the use of the same for manufacturing medicaments, pharmaceutical compositions comprising them and methods of treatment utilizing them
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.