Patent · US Expired

Starch derivatives, starch active substance conjugates, method for the production thereof and their use as medicaments

US7285661B2 · kind B2 · utility

15Cited by

1References

29Claims

0Family size

Assignee

Fresenius Kabi Deutschland GmbH · DE

Inventors

Klaus Sommermeyer · Rosbach, DE
Norbert Zander · Marburg, DE
Ronald Frank · Lehre, DE
Harald Conradt · Braunschweig, DE

Key dates

Filing date	Feb 20, 2003
Grant date	Oct 23, 2007
Priority date	—
Expiry date	Aug 17, 2024

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P31/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to starch derivatives of formula (I), in which: X represents a bromine or iodine atom; R″ represents a straight-chain or branched alkyl group, aryl group or aralkyl group, and; R—CO— represents an oxidized substituted or unsubstituted starch radical that is oxidized on the reducing terminal group to form a carboxylic acid. Starch derivatives of formula (I) can selectively couple to active substances containing SH groups and have a prolonged half-life period in the human body. The invention also relates to coupling products of compound (I) with active substances, to methods for the production thereof, and to their use as medicaments

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.