Bioadhesive nanoparticulate compositions having cationic surface stabilizers
US7288267B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 7, 2001 |
| Grant date | Oct 30, 2007 |
| Priority date | — |
| Expiry date | Jul 23, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/614
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Bioadhesive nanoparticulate compositions, comprising active agent particles and one or more cationic surface stabilizers, are described. The cationic surface stabilizers prevent aggregation of the nanoparticles and increase bioadhesion of the nanoparticles to biological substrates, such as an insect, teeth, bone, nails, chitin, feathers, scales, mucous, skin, hair, plant tissue, etc. The particles may consist of pharmacologically active compounds (e.g., drug compounds for human or veterinary use), agricultural chemicals (pesticides, herbicides, fertilizers, and the like), cosmetic agents, consumer products (coloring agents, flavors, or fragrances), or other materials which function by interacting with biological substrates. In addition, the invention relates to methods of preparing and using such bioadhesive nanoparticulate compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.