Substrate and method for measuring the electro-physiological properties of cell membranes
US7288785B2 · kind B2 · utility
5Cited by
3References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 17, 2003 |
| Grant date | Oct 30, 2007 |
| Priority date | — |
| Expiry date | Feb 15, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/48728
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a substantially planar substrate for use in patch clamp analysis of the electrophysiological properties of a cell membrane comprising a glycocalyx, wherein the substrate comprises an aperture having a rim, the rim being adapted to form a gigaseal upon contact with the cell membrane, The invention further provides a method of making such a substrate and method for analysing the electrophysiological properties of a cell membrane comprising a glycocalyx.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.