CXCR4 chemokine receptor binding compounds
US7291631B2 · kind B2 · utility
42Cited by
6References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 12, 2004 |
| Grant date | Nov 6, 2007 |
| Priority date | — |
| Expiry date | Apr 25, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds that bind to chemokine receptors, and having the formulawherein each A, X, Y, R1, R2 and R3 are substituents. The present invention also relates to methods of using such compounds, such as in treating HIV infection and inflammatory conditions such as rheumatoid arthritis. Furthermore, the present invention relates to methods to elevate progenitor and stem cell counts, as well as methods to elevate white blood cell counts, using such compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.