3-amido-1,2-benzoisoxazole derivatives, process for preparation, and use thereof
US7291638B2 · kind B2 · utility
27Cited by
1References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 5, 2002 |
| Grant date | Nov 6, 2007 |
| Priority date | — |
| Expiry date | Sep 11, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P19/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to 3-amido-1,2-benzoisoxazole derivatives and their salts represented by formula 1, processes for preparation and usees thereof. More particularly, it relates to a method for improving its bioavailability introducing amino acid residue to the amine group of a 3-amido-1,2-benzoisoxazole. The compounds according to the present invention are used as an antagonist against Leukotriene-B-4 receptor, an inhibitor or therapeutics of osteoroposis, thus inhibiting osteolysis and stimulating osteogensis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.