Nucleic acid constructs and cells, and methods utilizing same for modifying the electrophysiological function of excitable tissues
US7294333B1 · kind B1 · utility
3Cited by
7References
3Claims
0Family size
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Key dates
| Filing date | Oct 20, 2000 |
| Grant date | Nov 13, 2007 |
| Priority date | — |
| Expiry date | Oct 20, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/99
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of modifying the electrophysiological function of an excitable tissue region of an individual is provided. The method includes the step of implanting cells into the excitable tissue region. Each implanted cell is (a) capable of forming gap junctions with at least one cell of the excitable tissue region; and (b) capable of forming a functional ion channel or transporter, wherein the functional ion channel or transporter is capable of modifying the electrophysiological function of the excitable tissue region.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.