Substituted 8′-pyri(MI)dinyl-dihydrospiro-[cycloalkylamine]-pyrimido[1,2-a]pyrimidin-6-one derivatives
US7294631B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Jun 12, 2006 |
| Grant date | Nov 13, 2007 |
| Priority date | — |
| Expiry date | Jun 12, 2026 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/141
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a dihydrospiro-[cycloalkylamine]-pyrimidone derivative represented by formula (I) or a salt thereof:wherein X, Y, R1, R2, R3, R4, o, m, n, p and q are as defined herein. The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β, such as Alzheimer disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.