1,3-Diamino-2-hydroxypropane pro-drug derivatives
US7294642B2 · kind B2 · utility
5Cited by
1References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 8, 2003 |
| Grant date | Nov 13, 2007 |
| Priority date | — |
| Expiry date | Mar 2, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds of formula (AA) (I) and (X):useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.