Method for preparing anti-MIF antibodies
US7294753B2 · kind B2 · utility
12Cited by
1References
12Claims
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Assignee
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Key dates
| Filing date | Jun 3, 2005 |
| Grant date | Nov 13, 2007 |
| Priority date | — |
| Expiry date | Sep 8, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/505
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The specification provides methods of preparing high-affinity antibodies to a macrophage migration inhibitory factor (MIF) in animals in which the MIF gene has been homozygously knocked-out (MIF−/−). Also provided are methods of preparing hybridomas which produce the anti-MIF antibodies, methods of administering the antibodies to treat inflammatory or cancerous conditions and/or diseases modulated by MIF, as well as compositions comprising said high-affinity anti-MIF antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.