Creation of variable length and sequence linker regions for dual-domain or multi-domain molecules
US7297478B1 · kind B1 · utility
4Cited by
10References
2Claims
0Family size
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Key dates
| Filing date | Sep 22, 2000 |
| Grant date | Nov 20, 2007 |
| Priority date | — |
| Expiry date | Oct 29, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/1034
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed are methods and compositions for creating a DNA, RNA or protein molecule with two or more nucleic acid or polypeptide domains, respectively, joined by a linker region. These methods are used to generate random linker libraries of nucleic acids that encode dual-domain or multi-domain polypeptides. The linker regions are characterized by both length and sequence variability.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.