Methods of identifying reduced internalization transmembrane receptor agonists
US7297503B2 · kind B2 · utility
2Cited by
6References
46Claims
0Family size
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Key dates
| Filing date | Oct 24, 2003 |
| Grant date | Nov 20, 2007 |
| Priority date | — |
| Expiry date | Apr 12, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Described herein are methods of identifying a transmembrane receptor (TMR) agonist and compounds identified by this method. The TMR agonist (TMRA) is capable of activating TMR signaling while exhibiting reduced TMR internalization over a control compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.