Antagonists of MCP-1 function and methods of use thereof
US7297696B2 · kind B2 · utility
9Cited by
8References
33Claims
0Family size
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Key dates
| Filing date | Oct 19, 2004 |
| Grant date | Nov 20, 2007 |
| Priority date | — |
| Expiry date | Sep 12, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds which are antagonists of MCP-1 function and are useful in the prevention or treatment of chronic or acute inflammatory or autoimmune diseases, especially those associated with aberrant lymphocyte or monocyte accumulation such as arthritis, asthma, atherosclerosis, diabetic nephropathy, inflammatory bowel disease, Crohn's disease, multiple sclerosis, nephrtitis, pancreatitis, pulmonary fibrosis, psoriasis, restenosis, and transplant rejection; pharmaceutical compositions comprising these compounds; and the use of these compounds and compositions in the prevention or treatment of such diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.