Process for preparing N6 substituted aminopurine ribofuranose nucleosides
US7297787B2 · kind B2 · utility
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Key dates
| Filing date | Mar 19, 2002 |
| Grant date | Nov 20, 2007 |
| Priority date | — |
| Expiry date | Mar 2, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An improved process for preparing N6 -substituted aminopurine ribofuranose nucleosides. Compounds of this type are known to be usefull in the prepartation of compounds having activitity at adenosine receptors, e.g. Adenosine A1 receptor. The process comprises the step of reacting a 6-halopurine ribofuranose nucleoside with an amine in the presence of CaCO3 , wherein acid is added to the reaction mixture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.