Molecules of the pyrin domain protein family and uses thereof
US7300749B2 · kind B2 · utility
0Cited by
1References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 22, 2002 |
| Grant date | Nov 27, 2007 |
| Priority date | — |
| Expiry date | Sep 12, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Diagnostic, screening and therapeutic methods utilizing NBS-1 and PYRIN-1 are disclosed. The methods take advantage of the interactions between NBS-1 or PYRIN-1 and various proteins involved in apoptotic and inflammatory signaling pathways. Also disclosed are methods for identifying modulators of ASC and NF-κB.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.