Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US7301009B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 2, 2003 |
| Grant date | Nov 27, 2007 |
| Priority date | — |
| Expiry date | May 16, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/726
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Isolated or biologically pure taste receptors comprised of at least one T1R1 and T1R3 polypeptide and compositions containing are provided. These taste receptors specifically bind to and/or are specifically activated by umami taste stimuli such as glutamate compounds. These taste receptors are useful in screening assays for identifying compounds that elicit or modulate (enhance or inhibit) umami taste. Such compounds can be used as additives and flavorants to improve the taste of compositions for human or animal consumption. In preferred embodiments, the T1R1/T1R3 receptor will be comprised of human T1R1/human T1R3 expressed in association with a suitable G protein, e.g. Gα15.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.