MVA expressing modified HIV envelope, gag, and pol genes

US7303754B2 · kind B2 · utility

Assignees

• The Government of the United States of American, as represented by the Secretary, Department of Health and Human Services · US
• The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. · US
• The United States of America, as represented by the Secretary, Department of the Army · US

Inventors

• Bernard Moss · Bethesda, US
• Patricia Earl · Bethesda, US
• Linda Wyatt · Rockville, US
• Leigh Anne Eller · Kampala, UG
• Thomas C. VanCott · Brookeville, US
• Matthew Edward Harris · Poway, US

Key dates

• Filing date: Sep 28, 2005
• Grant date: Dec 4, 2007
• Expiry date: Sep 28, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2830/60
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides modified virus Ankara (MVA), a replication-deficient strain of vaccinia virus, expressing human immunodeficiency virus (HIV) env, gag, and pol genes.