Local vascular delivery of mycophenolic acid in combination with rapamycin to prevent restenosis following vascular injury
US7303758B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 20, 2004 |
| Grant date | Dec 4, 2007 |
| Priority date | — |
| Expiry date | Mar 16, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2420/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascu…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.