Compositions for conjugated estrogens and associated methods
US7303763B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Sep 22, 2003 |
| Grant date | Dec 4, 2007 |
| Priority date | — |
| Expiry date | Nov 14, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P19/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Oral conjugated estrogen formulations are disclosed and described. In one aspect, the oral formulation may be a tablet having a core and one or more coatings thereon. In addition to conjugated estrogen ingredients, the core may include one or more organic excipients and one or more inorganic excipients. In one aspect, the organic excipients may include less than about 20% w/w of a cellulose ingredient, and less than about 50% w/w of a sugar ingredient. In another aspect, the inorganic excipients may include less than about 10% w/w of a calcium phosphate tribasic ingredient. In yet another aspect, the formulation does not crack when stored at about 40° C. and about 75% relative humidity for about 2 months.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.