Nano-chem-FET based biosensors
US7303875B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 9, 2003 |
| Grant date | Dec 4, 2007 |
| Priority date | — |
| Expiry date | Sep 28, 2024 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/144444
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods of detecting components of interest, e.g., nucleic acids and sugars, are provided. The methods comprise contacting one or more nanowires comprising a functional group with a sample containing the component or components of interest. In one embodiment, the functional group comprises a hairpin oligonucleotide, e.g., a hairpin that changes conformation upon binding the component of interest, e.g., a nucleic acid. The change in conformation produces a change in charge that is detected. In another embodiment, the functional group comprises an enzyme, e.g., glucose oxidase, which produces a change in pH when glucose is present in a sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.