Competent bacteria
US7303906B2 · kind B2 · utility
10Cited by
15References
7Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Sep 5, 2003 |
| Grant date | Dec 4, 2007 |
| Priority date | — |
| Expiry date | Sep 5, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N1/08
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention discloses that a bacterium having a genome that is genetically engineered to be at least 10% smaller than the genome of its native parent strain has better transformation competence. Specific E. coli strains, having significantly reduced genome sizes, are disclosed which are highly transformation competent. A medium and methodology is taught which enables transformation efficiencies to be increased further.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.