Multi-sided immersion formation of composite structures and method
US7309458B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 20, 2003 |
| Grant date | Dec 18, 2007 |
| Priority date | — |
| Expiry date | Oct 26, 2024 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/255
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Sample preparation device and method for desalting and concentrating samples prior to further analysis such as by MALDI TOF and/or electro-spray ionization (ESI) mass spectrometry. The device in accordance with an embodiment of the present invention contains a three dimensional structure preferably comprising a plurality of sorptive particles entrapped in a porous polymer matrix so as to form a device capable of carrying out solid phase extraction. The device is manufactured by introducing casting solution containing polymer and optionally particles into a housing, and subsequently exposing the device to a quench bath for a time sufficient to allow for solvent exchange and precipitation to form the composite structure in the housing. The present invention is also directed towards a method of sample preparation using the device of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.