Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste
US7309577B2 · kind B2 · utility
59Cited by
3References
61Claims
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Key dates
| Filing date | Dec 3, 2003 |
| Grant date | Dec 18, 2007 |
| Priority date | — |
| Expiry date | Mar 19, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/726
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Binding assays for identifying compounds that induce or modulate the T1R1/T1R3 (umami) receptor-associated taste are provided. These binding assays detect the specific binding of a compound to a T1R1/T1R3 (umami) taste receptor or detect the modulation (inhibition or enhancement) of the binding of another compound, e.g., L-glutamate, L-aspartate or lactisole to a T1R1/T1R3 umami taste receptor. Compounds that are identified in these binding assays have potential application as T1R1/T1R3 umami taste modulators and therefore can be used as flavor additives in compositions for human or animal consumption.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.