Preventives and remedies for pulmonary hypertension
US7309693B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | May 25, 2001 |
| Grant date | Dec 18, 2007 |
| Priority date | — |
| Expiry date | Dec 31, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/505
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a prophylactic and/or therapeutic agent for pulmonary hypertension, comprising an antagonistic mutein of MCP-1 or a salt thereof, a DNA molecule comprising a nucleotide sequence encoding the antagonistic mutein of MCP-1, or a neutralizing antibody against MCP-1. The antagonistic mutein of MCP-1 or a salt thereof, the DNA molecule having a nucleotide sequence encoding the antagonistic mutein of MCP-1, or the neutralizing antibody against MCP-1 has hypotensive activity, and thus is useful as a pharmaceutical agent for preventing and/or treating pulmonary hypertension (primary pulmonary hypertension, in particular).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.