Patent · US Expired

3-Quinuclidinyl amino-substituted biaryl derivatives

US7309699B2 · kind B2 · utility

12Cited by
2References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 17, 2004
Grant dateDec 18, 2007
Priority date
Expiry dateFeb 10, 2025

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P25/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of formula (I)wherein A is N or N+—O−; n is 0, 1, or 2; Y is O, S, —NH—, and —N-alkyl-; Ar1 is both 6-membered aromatic rings; Ar2 is 5- or 6-membered aromatic rings with a —NR8R9 group, as defined herein. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.