Crystalline micronisate, process for the manufacture thereof and use thereof for the preparation of a medicament

US7309707B2 · kind B2 · utility

Assignee

• BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG · DE

Inventors

• Helmut Bender · Pleidelsheim, DE
• Hagen Graebner · Ingelheim am Rhein, DE
• Konrad Schindler · Ingelheim am Rhein, DE
• Michael Trunk · Ingelheim am Rhein, DE
• Michael Walz · Friedberg, DE

Key dates

• Filing date: Mar 10, 2003
• Grant date: Dec 18, 2007
• Expiry date: Mar 10, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/0075
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a crystalline micronisate of (1α,2β,4β,5α,7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane-bromide, processes for preparing it and its use for preparing a pharmaceutical composition, particularly for preparing a pharmaceutical composition with an anticholinergic activity.