Patent · US Expired

Multilayer hydrodynamic sheath flow structure

US7311476B2 · kind B2 · utility

61Cited by
10References
31Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 1, 2004
Grant dateDec 25, 2007
Priority date
Expiry dateNov 1, 2024

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N15/1409
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A microfabricated sheath flow structure for producing a sheath flow includes a primary sheath flow channel for conveying a sheath fluid, a sample inlet for injecting a sample into the sheath fluid in the primary sheath flow channel, a primary focusing region for focusing the sample within the sheath fluid and a secondary focusing region for providing additional focusing of the sample within the sheath fluid. The secondary focusing region may be formed by a flow channel intersecting the primary sheath flow channel to inject additional sheath fluid into the primary sheath flow channel from a selected direction. A sheath flow system may comprise a plurality of sheath flow structures operating in parallel on a microfluidic chip.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.